Figure 1. Magnetic resonance imaging study of a 5-year-old Yorkshire Terrier diagnosed with presumptive Leigh-like subacute necrotising encephalopathy. T2-weighted transverse (A) and T1 weighted transverse (B) dorsal pre-contrast (C) and dorsal post-contrast images at the level of the thalamus. D) Bilateral, symmetrical, well circumscribed areas within the mid-thalamus were identified (indicated by arrows), presumed to be the lateral geniculate nuclei.

A review of mitochondrial disease in dogs

The aetiology of mitochondrial diseases classically involves inheritable genetic mutations in mtDNA and nDNA coding for mitochondrial components, as well as de novo mutations within the individual...